Due to its crystalline structure, absorption of DIM is minimal when given orally. For this reason, Bio-DIM is manufactured utilizing an all-natural process and formulation that improves the absorption of DIM. DIM is the end result of the body breaking down cruciferous vegetables, known for their cancer protection.


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Please note: This item has been discontinued. You can purchase Designs for Health version DIM-Evail™ softgels

Discover the Health Benefits of Bio-DIM

Plant indoles (also called glucosinolates) found in cruciferous vegetables provide health benefits to humans. Cruciferous vegetables are known for their cancer protection. Two such indoles provided by cruciferous vegetables are I3C (Indole-3-Carbinol) and DIM (Diindolylmethane). DIM is not naturally present in these plants. It gets released with the help of enzymes upon crushing of the broccoli, cauliflower, cabbage or brussel sprouts or during human digestion. Stomach acid, or HCl, can also aid the joining of two indole 3 carbinols to make diindolylmethane. Lack of HCl will hinder one’s ability to make DIM from I3C.

Basically, DIM is two molecules of I3C combined together. I3C in a capsule is not shelf stable because it is sensitive to light, heat and moisture. I3C is irritating to the stomach and research tells us that it can have very negative side effects in doses over 300 mg daily such as dizziness and unsteady gait which may be due to nervous system toxicity. One study shows evidence that 90% of orally consumed I3C converts to other compounds. Perhaps it is these other compounds that cause these side effects. One compound I3C converts to is ICZ, or indolocarbazole. This compound causes DNA damage. DIM studies show no toxicity when given triple the dose in humans.

Supplement Facts

One Bottle: 60 Softgels

Serving Size: 1 Softgel

Number of servings: 60 Daily Servings

Diindolylmethane (DIM) 100 mg

Non-Medical Ingredients:Medium chain triglycerides, vitamin E, sunflower lecithin. Gelatin, purified water, glycerine, tumeric (softgel ingredients).